Products
G3BP1 antibody
- Product Name
- G3BP1 antibody
- Catalogue No.
- FNab03267
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- GTPase activating protein(SH3 domain) binding protein 1
- Alternative Names
- G3BP antibody
- UniProt ID
- Q13283
- Observed MW
- 55-60 kDa
Application
- Tested Applications
- ELISA, WB, IP, IF, IHC, FC
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab03267(G3BP1 antibody) at dilution of 1:1000
IP Result of anti-G3BP1 (IP:FNab03267, 3ug; Detection:FNab03267 1:1000) with HEK-293 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human testis slide using FNab03267(G3BP1 Antibody) at dilution of 1:50
- Background
- May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP-and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'-and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
