Products
FXN antibody
- Product Name
- FXN antibody
- Catalogue No.
- FNab03255
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- frataxin
- Alternative Names
- CyaY antibody, d FXN antibody, FA antibody, FARR antibody, frataxin antibody, Frataxin(81 210) antibody, Frataxin antibody, mitochondrial antibody, FRDA antibody, Friedreich ataxia protein antibody, FXN antibody, i FXN Frataxin(56 210) antibody, m56 FXN Frataxin(78 210) antibody, m78 FXN Frataxin mature form antibody, m81 FXN antibody, X25 antibody
- UniProt ID
- Q16595
- Observed MW
- 14 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
K562 cells were subjected to SDS PAGE followed by western blot with FNab03255(FXN antibody) at dilution of 1:1000
- Background
- FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
