human heart tissue were subjected to SDS PAGE followed by western blot with FNab03227(FRZB antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab03227(FRZB antibody) at dilution of 1:100
Background
Soluble frizzled-related proteins(sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.