Products
FRS2 antibody
- Product Name
- FRS2 antibody
- Catalogue No.
- FNab03225
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fibroblast growth factor receptor substrate 2
- Alternative Names
- FGFR signaling adaptor SNT antibody, FGFR substrate 2 antibody, FRS2 antibody, FRS2A antibody, FRS2alpha antibody, SNT antibody, SNT 1 antibody, SNT1 antibody
- UniProt ID
- Q8WU20
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IF
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab03225(FRS2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03225(FRS2 antibody) at dilution of 1:50
- Background
- Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
