Products
FOLR1 antibody
- Product Name
- FOLR1 antibody
- Catalogue No.
- FNab03184
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- folate receptor 1
- Alternative Names
- Adult folate binding protein antibody, FBP antibody, Folate receptor 1 antibody, folate receptor 1(adult) antibody, Folate receptor alpha antibody, Folate receptor antibody, adult antibody, FOLR antibody, FOLR1 antibody, FR alpha antibody
- UniProt ID
- P15328
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IF,IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03184(FOLR1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03184(FOLR1 Antibody) at dilution of 1:100
Immunofluorescent analysis of HeLa cells using FNab03184 (FOLR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
