Products
FMN2 antibody
- Product Name
- FMN2 antibody
- Catalogue No.
- FNab03166
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- formin 2
- Alternative Names
- FMN2 antibody, formin 2 antibody
- UniProt ID
- Q9NZ56
- Observed MW
- 195 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:50-1:500
Validated Images
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab03166(FMN2 antibody) at dilution of 1:50
- Background
- Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis(By similarity). Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.
