K-562 cells were subjected to SDS PAGE followed by western blot with FNab03141(FKBP5 antibody) at dilution of 1:1000
IP Result of anti-FKBP5 (IP:FNab03141, 3ug; Detection:FNab03141 1:1000) with K-562 cells lysate 1500ug.
Immunohistochemistry of paraffin-embedded human colon cancer using FNab03141(FKBP5 antibody) at dilution of 1:50
Background
Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90(HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.