Products
FIS1 antibody
- Product Name
- FIS1 antibody
- Catalogue No.
- FNab03132
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fission 1(mitochondrial outer membrane) homolog
- Alternative Names
- CGI 135 antibody, FIS1 antibody, FIS1 homolog antibody, hFis1 antibody, TPR repeat protein 11 antibody, TTC11 antibody
- UniProt ID
- Q9Y3D6
- Observed MW
- 17 kDa
Application
- Tested Applications
- ELISA, IHC, IF, IP, WB
- Recommended dilution
- WB: 1:1000-1:3000; IHC: 1:10-1:100; IF: 1:50-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03132(FIS1 antibody) at dilution of 1:2000
IP Result of anti-FIS1 (IP:FNab03132, 3ug; Detection:FNab03132 1:500) with HeLa cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human brain using FNab03132(FIS1 antibody) at dilution of 1:50
- Background
- Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1(DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
