Products
Fibronectin antibody
- Product Name
- Fibronectin antibody
- Catalogue No.
- FNab03122
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- fibronectin 1
- Alternative Names
- CIG antibody, Cold insoluble globulin antibody, DKFZp686F10164 antibody, DKFZp686H0342 antibody, DKFZp686I1370 antibody, DKFZp686O13149 antibody, ED B antibody, Fibronectin antibody, fibronectin 1 antibody, FINC antibody, FN antibody, FN1 antibody, FNZ antibody, GFND antibody, GFND2 antibody, LETS antibody, MSF antibody
- UniProt ID
- P02751
- Observed MW
- 260 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:5000; IHC: 1:50-1:200
Validated Images
U-87MG cells were subjected to SDS PAGE followed by western blot with FNab03122(FN1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab03122(FN1 antibody) at dilution of 1:50
- Background
- Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)
