FEM1B antibody

Synonyms:Protein fem-1 homolog B (FEM1b)|FEM1-beta|Fem-1-like death receptor-binding protein alpha|Fem-1-like in apoptotic pathway protein alpha (F1A-alpha)|FEM1B|F1AA|KIAA0396 antibody
Catalogue No.:FNab03072Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FEM1B antibody
Catalogue No.
FNab03072
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
fem-1 homolog b
Alternative Names
Protein fem-1 homolog B (FEM1b)|FEM1-beta|Fem-1-like death receptor-binding protein alpha|Fem-1-like in apoptotic pathway protein alpha (F1A-alpha)|FEM1B|F1AA|KIAA0396 antibody
UniProt ID
Q9UK73
Observed MW
70 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03072(FEM1B antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03072(FEM1B antibody) at dilution of 1:100
Background
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.