Products
FBXO7 antibody
- Product Name
- FBXO7 antibody
- Catalogue No.
- FNab03049
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- F-box protein 7
- Alternative Names
- FBX7 antibody
- UniProt ID
- Q9Y3I1
- Observed MW
- 58.5 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03049(FBXO7 antibody) at dilution of 1:1000
IP Result of anti-FBXO7 (IP:FNab03049, 3ug; Detection:FNab03049 1:800) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03049(FBXO7 antibody) at dilution of 1:100
- Background
- Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
