FBXO22 antibody

Synonyms:FBX22 antibody
Catalogue No.:FNab03041Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FBXO22 antibody
Catalogue No.
FNab03041
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
F-box protein 22
Alternative Names
FBX22 antibody
UniProt ID
Q8NEZ5
Observed MW
45 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03041(FBXO22 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human tonsil using FNab03041(FBXO22 antibody) at dilution of 1:50
Background
Substrate-recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin(ACTN2) and filamin-C(FLNC), essential for maintenance of normal contractile function.