FAM3C antibody

Synonyms:FAM3C antibody, Protein FAM3C antibody, GS3786 antibody, Interleukin like EMT inducer antibody, ILEI antibody
Catalogue No.:FNab02982Reactivity:Human
Host:MouseTested Application:ELISA, WB, IHC, IF
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
FAM3C antibody
Catalogue No.
FNab02982
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
2A10
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
family with sequence similarity 3, member C
Alternative Names
FAM3C antibody, Protein FAM3C antibody, GS3786 antibody, Interleukin like EMT inducer antibody, ILEI antibody
UniProt ID
Q92520
Observed MW
25kd
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Validated Images
fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab02982(FAM3C Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02982(FAM3C Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HepG2 cells using FNab02982 (FAM3C antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)
Background
FAM3C, also known as ILEI, is a secreted protein belonging to the cytokine-like protein family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. A change in expression of this protein has been noted in pancreatic cancer-derived cells. FAM3C has been involved in the epithelial to mesenchymal transition, and retinal laminar formation processes in vertebrates. Also, FAM3C may play an important role in inner ear development and thus be involved in cell differentiation and proliferation during inner ear embryogenesis.