Products
FAF2 antibody
- Product Name
- FAF2 antibody
- Catalogue No.
- FNab02947
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Fas associated factor family member 2
- Alternative Names
- ETEA antibody, KIAA0887 antibody, UBXD8 antibody, UBXN3B antibody
- UniProt ID
- Q96CS3
- Observed MW
- 53 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02947(FAF2 antibody) at dilution of 1:1000
IP Result of anti-FAF2 (IP:FNab02947, 3ug; Detection:FNab02947 1:1000) with mouse brain tissue lysate 5000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab02947(FAF2 antibody) at dilution of 1:50
- Background
- Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).
