NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab02910(EXT2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02910(EXT2 antibody) at dilution of 1:50
Background
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).