EXT2 antibody

Synonyms:exostoses (multiple) 2 antibody, Exostosin 2 antibody, EXT2 antibody, Multiple exostoses protein 2 antibody, SOTV antibody
Catalogue No.:FNab02910Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
EXT2 antibody
Catalogue No.
FNab02910
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
exostoses(multiple) 2
Alternative Names
exostoses (multiple) 2 antibody, Exostosin 2 antibody, EXT2 antibody, Multiple exostoses protein 2 antibody, SOTV antibody
UniProt ID
Q93063
Observed MW
82kd
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab02910(EXT2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02910(EXT2 antibody) at dilution of 1:50
Background
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).