Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02891(EXO1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab02891(EXO1 antibody) at dilution of 1:100
Background
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.