Products
EXD2 antibody
- Product Name
- EXD2 antibody
- Catalogue No.
- FNab02890
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- exonuclease 3'-5' domain containing 2
- Alternative Names
- C14orf114 antibody, antibody
- UniProt ID
- Q9NVH0
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02890(EXD2 antibody) at dilution of 1:300
IP Result of anti-EXD2 (IP:FNab02890, 3ug; Detection:FNab02890 1:300) with mouse lung tissue lysate 5160ug.
Immunohistochemistry of paraffin-embedded human testis using FNab02890(EXD2 antibody) at dilution of 1:50
- Background
- Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
