Products
ERLIN1 antibody
- Product Name
- ERLIN1 antibody
- Catalogue No.
- FNab02848
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ER lipid raft associated 1
- Alternative Names
- C10orf69 antibody, KE04 antibody, KEO4 antibody, SPFH1 antibody
- UniProt ID
- O75477
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
rat pancreas tissue were subjected to SDS PAGE followed by western blot with FNab02848(ERLIN1 antibody) at dilution of 1:500
IP Result of anti-ERLIN1 (IP:FNab02848, 3ug; Detection:FNab02848 1:1000) with mouse heart tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab02848(ERLIN1 antibody) at dilution of 1:100
- Background
- Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
