ERCC3 antibody

Synonyms:XPB antibody, XPBC antibody
Catalogue No.:FNab02834Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ERCC3 antibody
Catalogue No.
FNab02834
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Alternative Names
XPB antibody, XPBC antibody
UniProt ID
P19447
Observed MW
80 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02834(ERCC3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse lung using FNab02834(ERCC3 antibody) at dilution of 1:100
Background
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.