mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab02834(ERCC3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse lung using FNab02834(ERCC3 antibody) at dilution of 1:100
Background
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.