Products
ELOVL2 antibody
- Product Name
- ELOVL2 antibody
- Catalogue No.
- FNab02746
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- elongation of very long chain fatty acids(FEN1/Elo2, SUR4/Elo3, yeast)-like 2
- Alternative Names
- SSC2 antibody
- UniProt ID
- Q9NXB9
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:50 - 1:200
Validated Images
Immunohistochemistry of paraffin-embedded human testis using FNab02746(ELOVL2 antibody) at dilution of 1:50
- Background
- Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid(C20-and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
