rat brain tissue were subjected to SDS PAGE followed by western blot with FNab02742(ELMO2 antibody) at dilution of 1:1000
Background
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor(GEF) activity of DOCK1.