Products
EIF3B antibody
- Product Name
- EIF3B antibody
- Catalogue No.
- FNab02702
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- eukaryotic translation initiation factor 3, subunit B
- Alternative Names
- eIF 3 eta antibody, EIF3 ETA antibody, EIF3 P110 antibody, EIF3 P116 antibody, EIF3B antibody, EIF3S9 antibody, hPrt1 antibody, PRT1 antibody, Prt1 homolog antibody
- UniProt ID
- P55884
- Observed MW
- 120 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab02702(EIF3B antibody) at dilution of 1:1000
- Background
- Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).
