HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02689(EIF2A antibody) at dilution of 1:300
IP Result of anti-EIF2A (IP:FNab02689, 3ug; Detection:FNab02689 1:1000) with MCF-7 cells lysate 3250ug.
Immunohistochemistry of paraffin-embedded human prostate cancer using FNab02689(EIF2A antibody) at dilution of 1:50
Background
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.