DOPA decarboxylase antibody

Synonyms:AADC antibody, DDC antibody, DOPA decarboxylase antibody
Catalogue No.:FNab02510Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
DOPA decarboxylase antibody
Catalogue No.
FNab02510
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
dopa decarboxylase
Alternative Names
AADC antibody, DDC antibody, DOPA decarboxylase antibody
UniProt ID
P20711
Observed MW
54 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02510(DDC antibody) at dilution of 1:1000
IP Result of anti-DOPA decarboxylase (IP:FNab02510, 4ug; Detection:FNab02510 1:800) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02510(DDC Antibody) at dilution of 1:50
Background
Aromatic-L-amino-acid decarboxylase belongs to the pyridoxal-dependent aminotransferase superfamily.DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine(DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.DDC is the cause of aromatic L-amino-acid decarboxylase deficiency(AADCD).Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines.