mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02510(DDC antibody) at dilution of 1:1000
IP Result of anti-DOPA decarboxylase (IP:FNab02510, 4ug; Detection:FNab02510 1:800) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02510(DDC Antibody) at dilution of 1:50
Background
Aromatic-L-amino-acid decarboxylase belongs to the pyridoxal-dependent aminotransferase superfamily.DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine(DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.DDC is the cause of aromatic L-amino-acid decarboxylase deficiency(AADCD).Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines.