DOK4 antibody

Catalogue No.:FNab02503Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
DOK4 antibody
Catalogue No.
FNab02503
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
docking protein 4
UniProt ID
Q8TEW6
Observed MW
37 kDa
Application
Tested Applications
ELISA, IHC
Recommended dilution
IHC: 1:20-1:200
Validated Images
Immunohistochemical of paraffin-embedded human prostate cancer using FNab02503(DOK4 antibody) at dilution of 1:50
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway(By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.