Products
DNAJA1 antibody
- Product Name
- DNAJA1 antibody
- Catalogue No.
- FNab02439
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- DnaJ(Hsp40) homolog, subfamily A, member 1
- Alternative Names
- DJ 2 antibody, DjA1 antibody, DnaJ protein homolog 2 antibody, DNAJ2 antibody, DNAJA1 antibody, hDJ 2 antibody, HDJ2 antibody, Heat shock 40 kDa protein 4 antibody, Heat shock protein J2 antibody, HSDJ antibody, HSJ 2 antibody, HSJ2 antibody, HSPF4 antibody, Human DnaJ protein 2 antibody
- UniProt ID
- P31689
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02439(DNAJA1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02439(DNAJA1 antibody) at dilution of 1:50
- Background
- Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).
