Products
DLL4 antibody
- Product Name
- DLL4 antibody
- Catalogue No.
- FNab02416
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- delta-like 4(Drosophila)
- UniProt ID
- Q9NR61
- Observed MW
- 75-80 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02416(DLL4 antibody) at dilution of 1:300
IP result of anti-DLL4(IP:FNab02416, 4ug; Detection:FNab02416 1:300) with mouse lung tissue lysate 4000 ug
- Background
- Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
