Products
DGAT1 antibody
- Product Name
- DGAT1 antibody
- Catalogue No.
- FNab02349
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- diacylglycerol O-acyltransferase homolog 1(Mouse)
- Alternative Names
- AGRP1 antibody, DGAT antibody
- UniProt ID
- O75907
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab02349(DGAT1 Antibody) at dilution of 1:1000
IP Result of anti-DGAT1 (IP:FNab02349, 3ug; Detection:FNab02349 1:300) with mouse heart tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab02349(DGAT1 Antibody) at dilution of 1:50
- Background
- Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL(very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase(ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
