Products
DENND1A antibody
- Product Name
- DENND1A antibody
- Catalogue No.
- FNab02332
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- DENN/MADD domain containing 1A
- Alternative Names
- FAM31A antibody, KIAA1608 antibody
- UniProt ID
- Q8TEH3
- Observed MW
- 111 kDa, 64 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
SKOV-3 cells were subjected to SDS PAGE followed by western blot with FNab02332( DENND1A Antibody) at dilution of 1:600
- Background
- Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).
