HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02318(DDX58 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate tissue slide using FNab02318(DDX58 Antibody) at dilution of 1:100
Immunofluorescent analysis of U2OS cells using FNab02318 (DDX58 antibody) at dilution of 1:50.
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp(DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain(CARD). It is involved in viral double-stranded(ds) RNA recognition and the regulation of immune response.