DARS2 antibody

Catalogue No.:FNab02246Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
DARS2 antibody
Catalogue No.
FNab02246
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
aspartyl-tRNA synthetase 2, mitochondrial
UniProt ID
Q6PI48
Observed MW
74 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab02246(DARS2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab02246(DARS2 antibody) at dilution of 1:100
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).