MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02245(DARS antibody) at dilution of 1:1000
IP result of anti-DARS(IP:FNab02245, 4ug; Detection:FNab02245 1:300) with Jurkat cells lysate 4000 ug
Immunohistochemistry of paraffin-embedded mouse brain using FNab02245(DARS Antibody) at dilution of 1:100
Background
This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants.