mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02229(DAB2IP Antibody) at dilution of 1:1000
IP Result of anti-DAB2IP (IP:FNab02229, 4ug; Detection:FNab02229 1:1000) with mouse brain tissue lysate 4000ug.
Background
Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor(TNF), interferon(IFN) or lipopolysaccharide(LPS).