Products
Cysteine dioxygenase type 1 antibody
- Product Name
- Cysteine dioxygenase type 1 antibody
- Catalogue No.
- FNab02183
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cysteine dioxygenase, type I
- Alternative Names
- CDO antibody, CDO I antibody, CDO1 antibody, Cysteine dioxygenase type 1 antibody, cysteine dioxygenase antibody, type I antibody
- UniProt ID
- Q16878
- Observed MW
- 23 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02183(CDO1 antibody) at dilution of 1:600
IP Result of anti-CDO1 (IP:FNab02183, 3ug; Detection:FNab02183 1:600) with mouse liver tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02183(CDO1 antibody) at dilution of 1:100
- Background
- CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid(3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase(CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO(23?kDa, 25?kDa, and 68?kDa) have been claimed based upon separation and detection using S
