Products
CYP7B1 antibody
- Product Name
- CYP7B1 antibody
- Catalogue No.
- FNab02177
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 7, subfamily B, polypeptide 1
- Alternative Names
- CBAS3 antibody, CP7B antibody, CYP7B1 antibody, Cytochrome P450 7B1 antibody, Oxysterol 7 alpha hydroxylase antibody, SPG5A antibody
- UniProt ID
- O75881
- Observed MW
- 50-55 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab02177(CYP7B1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02177(CYP7B1 Antibody) at dilution of 1:50
- Background
- Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) from 25-hydroxycholesterol(PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells(By similarity).
