Products
CYP4F11 antibody
- Product Name
- CYP4F11 antibody
- Catalogue No.
- FNab02170
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 4, subfamily F, polypeptide 11
- UniProt ID
- Q9HBI6
- Observed MW
- 57kd
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab02170(CYP4F11 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver cancer using FNab02170(CYP4F11 antibody) at dilution of 1:100
- Background
- Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1(phylloquinone), and menaquinone-4(MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation(PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate(PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine(PubMed:15364545).
