Products
CYP2C8 antibody
- Product Name
- CYP2C8 antibody
- Catalogue No.
- FNab02156
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 2, subfamily C, polypeptide 8
- Alternative Names
- CPC8 antibody, CYP2C8 antibody, CYPIIC8 antibody, Cytochrome P450 2C8 antibody
- UniProt ID
- P10632
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:500-1:1000
Validated Images
Immunohistochemistry of paraffin-embedded human liver cancer using FNab02156( CYP2C8 antibody) at dilution of 1:500
- Background
- Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15-and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel(taxol).
