Products

anti- Cyclophilin A antibody

FNab02134 Catalogue No.
Synonyms
Cyclophilin A, Cyclosporin A binding protein, CYPA, CYPH, PPIA, PPIase A, Rotamase A
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC, IF, FC
Product Information
Product Name
anti- Cyclophilin A antibody
Catalogue No.
FNab02134
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Immunogen Information
Immunogen
peptidylprolyl isomerase A (cyclophilin A)
Synonyms
Cyclophilin A, Cyclosporin A binding protein, CYPA, CYPH, PPIA, PPIase A, Rotamase A
Observed MW
18 kDa
Application
Tested Application
ELISA, WB, IHC, IF, FC
Recommended dilution
WB: 1:500-1:3000; IHC: 1:20-1:200; IF: 1:10-1:100
Uniprot information
UniProt ID
P62937
Images
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02134 (CYPA antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells, using PPIA antibody FNab02134 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
K-562 cells were subjected to SDS PAGE followed by western blot with FNab02134 (CYPA antibody) at dilution of 1:1500