Products
Cyclophilin A antibody
- Product Name
- Cyclophilin A antibody
- Catalogue No.
- FNab02134
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- peptidylprolyl isomerase A(cyclophilin A)
- Alternative Names
- Cyclophilin A antibody, Cyclosporin A binding protein antibody, CYPA antibody, CYPH antibody, PPIA antibody, PPIase A antibody, Rotamase A antibody
- UniProt ID
- P62937
- Observed MW
- 18 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC
- Recommended dilution
- WB: 1:500-1:3000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab02134(CYPA antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02134(CYPA antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells, using PPIA antibody FNab02134 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
