Products
CXCR3B-specific antibody
Category:
Research Area:
Synonyms: | CD183 antibody, CKR L2 antibody, CMKAR3 antibody, CXC R3 antibody, CXCR 3 antibody, CXCR3 antibody, CXCR3A antibody, CXCR3B antibody, G protein coupled receptor 9 antibody, GPR9 antibody, IP 10 receptor antibody, IP10 R antibody, Mig R antibody, MigR antibody | ||
Catalogue No.: | FNab02101 | Reactivity: | Human |
Host: | Mouse | Tested Application: | ELISA, WB |
Clonality: | monoclonal | Isotype: | IgG1 |
- SPECIFICATIONS
- Product Name
- CXCR3B-specific antibody
- Catalogue No.
- FNab02101
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 6F7
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- chemokine(C-X-C motif) receptor 3
- Alternative Names
- CD183 antibody, CKR L2 antibody, CMKAR3 antibody, CXC R3 antibody, CXCR 3 antibody, CXCR3 antibody, CXCR3A antibody, CXCR3B antibody, G protein coupled receptor 9 antibody, GPR9 antibody, IP 10 receptor antibody, IP10 R antibody, Mig R antibody, MigR antibody
- UniProt ID
- P49682
- Observed MW
- 40 kDa +43 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:5000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02101(CXCR3B antibody) at dilution of 1:2000
- Background
- CXCR3(C-X-C chemokine receptor type 3) is a G protein-coupled, seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+ and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells(PMID: 16847335). CXCR3 binds and is activated by the three IFN-gamma-inducible chemokines: CXCL9, CXCL10, and CXCL11. Binding of these ligands to CXCR3 has been implicated in regulating T-cell infiltration during inflammation and tissue injury(PMID: 17250586). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms, CXCR3B, mediates the angiostatic activity of CXCR3 ligands and also acts as functional receptor for CXCL4(PMID:12782716). This monoclonal antibody is specific to CXCR3B.