Products
CUX1 antibody
- Product Name
- CUX1 antibody
- Catalogue No.
- FNab02083
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cut-like homeobox 1
- Alternative Names
- CASP antibody, CCAAT displacement protein antibody, CDP antibody, CDP/Cut antibody, CDP1 antibody, Clox antibody, COY1 antibody, cut like homeobox 1 antibody, CUTL1 antibody, CUX antibody, Cux/CDP antibody, CUX1 antibody, GOLIM6 antibody, Homeobox protein cut like 1 antibody, Homeobox protein cux 1 antibody, Nbla10317 antibody, p100 antibody, p110 antibody, p200 antibody, p75 antibody
- UniProt ID
- P39880
- Observed MW
- 80 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:1000-1:3000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02083(CUX1 antibody) at dilution of 1:1000
IP Result of anti-CUX1 (IP:FNab02083, 4ug; Detection:FNab02083 1:1000) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded mouse brain using FNab02083(CUX1 antibody) at dilution of 1:100
Immunofluorescent analysis of HepG2 cells, using FNab02083(CUX1 antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).
