Products
CTDSP2 antibody
- Product Name
- CTDSP2 antibody
- Catalogue No.
- FNab02051
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CTD(carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
- Alternative Names
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2|Nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2)|Protein OS-4|Small C-terminal domain phosphatase 2|Small CTD phosphatase 2 (SCP2)|CTDSP2|NIF2|OS4|SCP2 antibody
- UniProt ID
- O14595
- Observed MW
- 31 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab02051(CTDSP2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab02051(CTDSP2 antibody) at dilution of 1:50
- Background
- Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain(CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
