CTDSP2 antibody

Synonyms:Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2|Nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2)|Protein OS-4|Small C-terminal domain phosphatase 2|Small CTD phosphatase 2 (SCP2)|CTDSP2|NIF2|OS4|SCP2 antibody
Catalogue No.:FNab02051Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CTDSP2 antibody
Catalogue No.
FNab02051
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
CTD(carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Alternative Names
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2|Nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2)|Protein OS-4|Small C-terminal domain phosphatase 2|Small CTD phosphatase 2 (SCP2)|CTDSP2|NIF2|OS4|SCP2 antibody
UniProt ID
O14595
Observed MW
31 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab02051(CTDSP2 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab02051(CTDSP2 antibody) at dilution of 1:50
Background
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain(CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.