Products
CSPG4,NG2 antibody
- Product Name
- CSPG4,NG2 antibody
- Catalogue No.
- FNab02025
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- chondroitin sulfate proteoglycan 4
- Alternative Names
- CSPG4 antibody, HMW MAA antibody, MCSP antibody, MCSPG antibody, MEL CSPG antibody, MSK16 antibody, NG2 antibody
- UniProt ID
- Q6UVK1
- Observed MW
- 240-250 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
A375 cells were subjected to SDS PAGE followed by western blot with FNab02025(CSPG4,NG2 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab02025(CSPG4,NG2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
