Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01936(CPSF1 antibody) at dilution of 1:500
Background
Component of the cleavage and polyadenylation specificity factor(CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.