Products
CPLX1 antibody
- Product Name
- CPLX1 antibody
- Catalogue No.
- FNab01920
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- complexin 1
- Alternative Names
- complexin 1 antibody, Complexin I antibody, complexin1 antibody, CPLX1 antibody, CPX I antibody, CPX1 antibody, Synaphin 2 antibody
- UniProt ID
- O14810
- Observed MW
- 15-20 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01920(CPLX1 antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab01920(CPLX1 Antibody) at dilution of 1:50
- Background
- Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles(PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse(PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.
