Collagen Type VI antibody

Synonyms:COL6A1 antibody, collagen 6A1 antibody, Collagen alpha 1(VI) chain antibody, collagen antibody, type VI antibody, alpha 1 antibody, OPLL antibody
Catalogue No.:FNab01846Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Collagen Type VI antibody
Catalogue No.
FNab01846
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
collagen, type VI, alpha 1
Alternative Names
COL6A1 antibody, collagen 6A1 antibody, Collagen alpha 1(VI) chain antibody, collagen antibody, type VI antibody, alpha 1 antibody, OPLL antibody
UniProt ID
P12109
Observed MW
140 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab01846(COL6A1 Antibody) at dilution of 1:600
IP Result of anti-Collagen Type VI (IP: FNab01846, 4ug; Detection: FNab01846 1:500) with mouse heart tissue lysate 8000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab01846(COL6A1 antibody) at dilution of 1:100
Background
Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts(PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.