HL-60 cells were subjected to SDS PAGE followed by western blot with FNab01759( CLIC1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab01759( CLIC1 Antibody) at dilution of 1:50
Background
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.