Products
CLEC4M antibody
- Product Name
- CLEC4M antibody
- Catalogue No.
- FNab01757
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- C-type lectin domain family 4, member M
- Alternative Names
- CD209L antibody, CD209L1 antibody, CD299 antibody
- UniProt ID
- Q9H2X3
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01757(CLEC4M Antibody) at dilution of 1:3000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01757(CLEC4M Antibody) at dilution of 1:50
- Background
- Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus(PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus(PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1(PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E(PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5(PubMed:12433371). Acts as an attachment receptor for influenzavirus(PubMed:21191006). Acts as an attachment receptor for SARS coronavirus(PubMed:15479853). Acts as an attachment receptor for west-nile virus(PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus(PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein(PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule(PubMed:21203928).
