Products
CIT antibody
- Product Name
- CIT antibody
- Catalogue No.
- FNab01720
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- citron(rho-interacting, serine/threonine kinase 21)
- Alternative Names
- CRIK antibody, KIAA0949 antibody, STK21 antibody
- UniProt ID
- O14578
- Observed MW
- 230kd
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:10-1:100
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab01720(CIT antibody) at dilution of 1:600
- Background
- Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
