Products
CISD2 antibody
- Product Name
- CISD2 antibody
- Catalogue No.
- FNab01718
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CDGSH iron sulfur domain 2
- Alternative Names
- CDGSH2 antibody, ERIS antibody, ZCD2 antibody
- UniProt ID
- Q8N5K1
- Observed MW
- 13-15 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01718(CISD2 antibody) at dilution of 1:1000
IP Result of anti-CISD2 (IP:FNab01718, 3ug; Detection:FNab01718 1:700) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab01718(CISD2 antibody) at dilution of 1:100
- Background
- Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
